Aspartate-aminopeptidase activity during the estrous cycle and the pregnancy in rat brain and pituitary gland.

J M de Gandarias, J Irazusta, E Echevarria, L Casis
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引用次数: 1

Abstract

The present report describes the activity of aspartate aminopeptidase, in 9 brain areas and in the pituitary gland, during the estrous cycle and several stages of pregnancy of the rat. The quantitation of the enzyme activity was performed by measuring the rate of hydrolysis of the chromogenic substrate Asp-beta-naphthylamide. Aspartate aminopeptidase activity, in the pituitary gland and in several limbic areas, was found to be greater in cyclic than in pregnant rats. However the enzyme activity did not change significantly during either the estrous cycle and pregnancy.

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大鼠脑和脑垂体发情周期与妊娠期天冬氨酸氨基肽酶活性的关系。
本报告描述了天冬氨酸氨基肽酶的活性,在9个脑区和脑垂体,在发情周期和怀孕的几个阶段的大鼠。酶活性的定量是通过测定显色底物asp - β -萘酰胺的水解速率来实现的。天冬氨酸氨基肽酶活性,在脑垂体和几个边缘区域,被发现是更大的循环比怀孕的大鼠。然而,在发情周期和怀孕期间,酶活性没有明显变化。
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