{"title":"[Testing for immunomodulating effects of ethanol-water extracts of the above-ground parts of the plants Echinaceae (Moench) and Rudbeckia L].","authors":"M Bukovský, D Kostálová, R Magnusová, S Vaverková","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Ethanolic extracts of aerial parts of the plants Echinacea angustifolia DC, Echinacea purpurea L. (Moench), Rudbeckia fulgida var. sullivantii, Boyton et Beadle, and Rudbeckia speciosa Wenderoth show immunomodulating activity. The mice were treated in vivo for 5 days and the activity was tested for and observed on day 7. An immunostimulatory effect was observed on the phagocytic, metabolic and bactericidal activities of peritoneal macrophages. The ethanolic extracts of both Echinacea plants also increased the total weight of the spleens as compared to the effect of the Rudbeckia plants and the control group which received saline.</p>","PeriodicalId":9871,"journal":{"name":"Ceskoslovenska farmacie","volume":"42 5","pages":"228-31"},"PeriodicalIF":0.0000,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ceskoslovenska farmacie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Ethanolic extracts of aerial parts of the plants Echinacea angustifolia DC, Echinacea purpurea L. (Moench), Rudbeckia fulgida var. sullivantii, Boyton et Beadle, and Rudbeckia speciosa Wenderoth show immunomodulating activity. The mice were treated in vivo for 5 days and the activity was tested for and observed on day 7. An immunostimulatory effect was observed on the phagocytic, metabolic and bactericidal activities of peritoneal macrophages. The ethanolic extracts of both Echinacea plants also increased the total weight of the spleens as compared to the effect of the Rudbeckia plants and the control group which received saline.
[紫锥科植物(Moench)和Rudbeckia L .)地上部分乙醇水提取物的免疫调节作用试验]。
紫锥菊(Echinacea angustifolia DC)、紫锥菊(Echinacea purpurea L. (Moench))、紫锥菊(Rudbeckia fulgida var. sullivantii)、Boyton et Beadle和紫锥菊(Rudbeckia speciosa Wenderoth)的地上部分乙醇提取物具有免疫调节活性。小鼠体内给药5 d，第7天检测并观察活性。对腹腔巨噬细胞的吞噬、代谢和杀菌活性均有免疫刺激作用。与紫锥菊和生理盐水对照组相比，两种紫锥菊的乙醇提取物均增加了大鼠脾脏的总重量。
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