[In vitro activity of chemotherapeutic agents on the most common bacterial agents causing urinary infections].

O Lochmann, J Lochmannová, M Klimesová, O Nyc
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Abstract

The authors made an investigation of the contemporary position as regards the effectiveness of chemotherapeutic agents used for treatment of infections of the urinary pathways caused by the most frequently found infectious agents in out-patients, small Prague hospitals and the University hospital in Prague-Motol. The dominating infectious agent causing urinary infections remains E. coli. A serious feature is the increase of enterococcal infections in hospitals. As to the antibacterial effect, a dominant position is held by furantoin, in enterococcal infections in hospitals. high antibacterial activity of fluoroquinolones is, however, also associated with the responsibility to use them rationally.

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化疗药物对引起泌尿系统感染的最常见细菌的体外活性研究。
作者调查了用于治疗门诊病人、布拉格小医院和布拉格-摩托尔大学医院中最常见的感染性病原体引起的泌尿道感染的化疗药物的有效性。引起泌尿系统感染的主要感染因子仍然是大肠杆菌。一个严重的特点是医院内肠球菌感染的增加。在医院肠球菌感染中,呋喃妥因的抗菌作用占主导地位。然而,氟喹诺酮类药物的高抗菌活性也与合理使用它们的责任有关。
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