[The determination of tetanus antitoxin by the latex agglutination reaction].

Abstract

A new method to detect the protective value of antitetanic antibody in latex agglutination test (LAT) has been described. The new method is highly sensitive and fast, and requires no special equipment. The optimal conditions of sensibilization, latex types, test providing procedure have been selected. New LAT detects approximately 0.0015 IU antitoxin per ml. This method can be used to determine the state of immunization of population against tetanus and to detect the protective antibodies in production series of human and horse antitetanic immunoglobulins.