[Renal tubular acidosis in children].

Pediatrie Pub Date : 1993-01-01
F Cachat, V Froidevaux, J P Guignard
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Abstract

Renal tubular acidosis represents a heterogenous group of disorders with various etiologies and mechanisms. The physiopathologic basis of each type of renal tubular acidosis is reviewed, focusing on the laboratory investigations necessary to define the nature of the hyperchloremic renal tubular acidosis. Clinically, the four types of renal tubular acidosis can be associated with complications such as osteomalacia, urolithiasis and failure to thrive. Very often, the chronic administration of alkali results in normal growth and development, and greatly reduces the risk of stone formation or nephrocalcinosis.

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[儿童肾小管酸中毒]。
肾小管酸中毒是一种具有不同病因和机制的异质性疾病。本文回顾了各种肾小管酸中毒的生理病理基础,重点介绍了确定高绿血症肾小管酸中毒性质所需的实验室检查。临床上,这四种类型的肾小管酸中毒可伴有骨软化症、尿石症和发育不良等并发症。通常,长期服用碱会导致正常的生长发育,并大大降低结石形成或肾钙质沉着症的风险。
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