[The effect of ionizing radiation on the resistance of rat pancreatic beta cells to streptozotocin].

Radiobiologiia Pub Date : 1993-03-01
G G Gatsko, S I Brilevskaia
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Abstract

The effect of subliminal streptozotocin doses of rat pancreas cells was studied 1 and 3 months after 1-Gy gamma irradiation. Streptozotocin injected to irradiated animals caused a drastic decrease in beta-cell function which was manifested by hyperglycemia and less intensive secretion and lesser content of insulin in isolated pancreatic islands, as compared to control.

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[电离辐射对大鼠胰腺β细胞对链脲佐菌素耐药性的影响]。
研究了1- gy γ照射后1、3个月阈下链脲佐菌素对大鼠胰腺细胞的影响。经放射动物注射链脲佐菌素后,β细胞功能急剧下降,表现为与对照组相比,离体胰岛出现高血糖、胰岛素分泌减弱和含量降低。
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