{"title":"[The effect of ionizing radiation on the resistance of rat pancreatic beta cells to streptozotocin].","authors":"G G Gatsko, S I Brilevskaia","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The effect of subliminal streptozotocin doses of rat pancreas cells was studied 1 and 3 months after 1-Gy gamma irradiation. Streptozotocin injected to irradiated animals caused a drastic decrease in beta-cell function which was manifested by hyperglycemia and less intensive secretion and lesser content of insulin in isolated pancreatic islands, as compared to control.</p>","PeriodicalId":20808,"journal":{"name":"Radiobiologiia","volume":"33 2","pages":"225-8"},"PeriodicalIF":0.0000,"publicationDate":"1993-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiobiologiia","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The effect of subliminal streptozotocin doses of rat pancreas cells was studied 1 and 3 months after 1-Gy gamma irradiation. Streptozotocin injected to irradiated animals caused a drastic decrease in beta-cell function which was manifested by hyperglycemia and less intensive secretion and lesser content of insulin in isolated pancreatic islands, as compared to control.
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