The problems of peritoneal dialysis in the management of chronic uraemia in Nigeria.

Tropical and geographical medicine Pub Date : 1995-01-01
A Arije, K S Akinlade, S Kadiri, O O Akinkugbe
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Abstract

The problems encountered in the use of peritoneal dialysis (PD) in the initial management of patients with chronic renal failure in Nigeria were highlighted, studying 23 patients (13 males and 10 females) aged between 15 and 68 years (mean age 36.4 years). Peritonitis was the most common complication, occurring in 16 (70%) of patients; effluent drainage obstruction in 11 patients (48%); haemorrhagic effluent in 10 patients (44%); fluid leak from catheter site infection in 7 patients (30%); accidental disconnection of line/catheter joint in 5 patients (22%); and catheter site infection in 2 patients (9%). A positive effluent culture was found in only 4 out of 18 cultured samples, with Klebsiella and Staphylococcus aureus being the organisms isolated. Dialysis was terminated in patients for the following reasons: financial constraints (8 patients), unresolving peritonitis (7 patients), drainage problems (3 patients), and clinical improvement (5 patients). The study concludes that PD in the management of chronic uraemia in developing countries, while producing clinical benefits in the majority of patients, is still not generally acceptable as a long-term treatment modality in view of the number of problems.

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腹膜透析在尼日利亚慢性尿毒症治疗中的问题。
研究了23例年龄在15 - 68岁(平均年龄36.4岁)的患者(13男10女),强调了在尼日利亚慢性肾衰竭患者的初始治疗中使用腹膜透析(PD)所遇到的问题。腹膜炎是最常见的并发症,16例(70%)患者发生腹膜炎;排出液梗阻11例(48%);出血性流出物10例(44%);7例(30%)因导管部位感染导致液体泄漏;5例(22%)患者意外断开线/导管关节;导管部位感染2例(9%)。在18个培养样本中,只有4个样本出水培养呈阳性,分离出克雷伯菌和金黄色葡萄球菌。患者因以下原因终止透析:经济拮据(8例),腹膜炎未解(7例),引流问题(3例),临床改善(5例)。该研究得出结论,在发展中国家,PD治疗慢性尿毒症虽然对大多数患者产生了临床益处,但鉴于问题的数量,PD作为一种长期治疗方式仍不被普遍接受。
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