[32 years of Senning's correction for transposition of the great vessels].

Swiss surgery. Supplement Pub Date : 1996-01-01
M Genoni, L von Segesser, M Wilhelm, U Arbenz, M Turina
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Abstract

Between 1962 and 1994 342 patients with transposition of the great arteries (TGA) were treated by atrial correction. Since 1992 the atrial switch operation is the treatment of choice for TGA. We reviewed our 32 year experience. Average age of the patients at operation was 69 months (7 days--8.5 years). 177/342 (52%) patients had a complex TGA: 74 patients with ventricular septal defect (VSD), 49 patients with pulmonary stenosis (PS) and 54 with both (VSD and PS). The 30 day mortality was for the whole series 15.7%. In the last 4 years 7.5%. The actuarial survival rate for all patients was 88% after 10 years and 82% after 20 years. For simple TGA 91% after 10 years and 83% after 20 years, for complex TGA 84% and 81%. The most important cause of death during our longterm observation were heart failure (19 patients) and sudden death (7 patients). Average follow-up for the whole group was 13.4 years. Most of the survivors are functionally symptom free (66% NYHA I) or they have slight symptoms (29% NYHA II). Only 5% were NYHA III or IV. Arterial switch operation has replaced the atrial correction for TGA. Nevertheless the longterm results after atrial correction remains encouraging. The main threat to the patients is the failure of the systemic ventricle.

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[森宁大血管转位校正32年]。
1962年至1994年间,342例大动脉转位(TGA)患者接受了心房矫正治疗。自1992年以来,心房开关手术是TGA的首选治疗方法。我们回顾了我们32年的经验。手术患者的平均年龄为69个月(7天-8.5岁)。177/342例(52%)患者有复杂TGA,其中室间隔缺损(VSD) 74例,肺动脉狭窄(PS) 49例,两者兼有(VSD和PS) 54例。全系列30天死亡率为15.7%。过去4年增长了7.5%。所有患者10年后的精算生存率为88%,20年后为82%。简单TGA 10年后为91%,20年后为83%,复杂TGA为84%,81%。在我们的长期观察中,最主要的死亡原因是心力衰竭(19例)和猝死(7例)。整个组的平均随访时间为13.4年。大多数幸存者无功能性症状(66%为NYHA I型)或症状轻微(29%为NYHA II型),只有5%为NYHA III型或IV型。动脉转换手术已取代心房矫正治疗TGA。然而,心房矫正后的长期结果仍然令人鼓舞。对患者的主要威胁是全身心室功能衰竭。
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