[Effect of water supply on the incidence of trachoma: preliminary results of a prospective study in Mali].

F Peyramaure, S Resnikoff, C Bagayoko, P Huguet, F De Liniers
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Abstract

This prospective study (January 1993-January 1994) was carried out in two groups of villages of the district of Ouelessebougou (Mali). The objective of the study was to assess the impact of installing water supply boreholes on the incidence of trachoma. A prospective group of 4 villages, where boreholes were sunk at the beginning of the study, was compared to a control group of 4 villages where there are no boreholes. The examination concerned children below the age of 10 years (N = 700) and was carried out using binocular loupes, according to the simplified procedure for trachoma grading proposed by the WHO. Our results show that in the prospective group, the annual rate of incidence of inflammatory trachoma was 8% (cl: 5.8-10.7) while in the control group it was 14% (cl: 9.6-10.9). RR: 0.58 (0.37-0.90). Likewise the rate of spontaneous healing was 12% (Cl: 9.1-14.9) in the prospective group and 5% (cl: 2.4-9) in the control group. Relative Risk was 2.60 (1.36-4.9). These statistically significant results show that the risk of contracting trachoma is reduced by half in the villages where a borehole has been sunk.

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[供水对沙眼发病率的影响:马里前瞻性研究的初步结果]。
这项前瞻性研究(1993年1月至1994年1月)在Ouelessebougou县(马里)的两组村庄进行。这项研究的目的是评估安装供水钻孔对沙眼发病率的影响。在研究开始时打孔的4个村庄与没有打孔的4个村庄的对照组进行了比较。检查涉及10岁以下儿童(N = 700),根据世界卫生组织建议的沙眼分级简化程序,使用双筒镜进行检查。我们的研究结果显示,在前瞻性组中,炎症性沙眼的年发病率为8% (cl: 5.8-10.7),而在对照组中为14% (cl: 9.6-10.9)。Rr: 0.58(0.37-0.90)。同样,预期组的自发愈合率为12% (Cl: 9.1-14.9),对照组为5% (Cl: 2.4-9)。相对危险度为2.60(1.36-4.9)。这些具有统计意义的结果表明,在打井的村庄,患沙眼的风险降低了一半。
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