An atypical neuroleptic drug in the treatment of behavioural disturbances and psychotic symptoms in elderly people.

B Robertsson, I Karlsson, L Eriksson, J O Olsson, H Olofsson, N O Jacobsson, G Arnell
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引用次数: 8

Abstract

The present study is a retrospective study of remoxipride therapy. A total of 103 patients, 65 years or older, with a DSM-III-R diagnosis of dementia or delirium, were included. They had all been treated with remoxipride because of psychotic symptoms or behavioural disturbances. The dose range of remoxipride was 50-300 mg, the median dose being 75 mg. The clinical effect was rated as good in two thirds of the patients, and side-effects were noted in one fourth. When psychomotor hyperactivity was the dominating problem, a good effect was rated in 81% of the patients. Side-effects were few and mild, the most common being tiredness; only 5 patients showed extrapyramidal symptoms.

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一种治疗老年人行为障碍和精神病症状的非典型抗精神病药物。
本研究是一项回顾性研究的remoxipride治疗。共纳入103例65岁及以上,DSM-III-R诊断为痴呆或谵妄的患者。由于精神病症状或行为障碍,他们都接受了remoxipride治疗。remoxipride的剂量范围为50 ~ 300 mg,中位剂量为75 mg。三分之二的患者临床效果良好,四分之一的患者出现了副作用。当精神运动性多动是主要问题时,81%的患者评价效果良好。副作用少且轻微,最常见的是疲劳;仅有5例出现锥体外系症状。
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