A nine-year follow up study of a population occupationally exposed to vinyl chloride monomer

A. Fučić , D. Barković , Verica Garaj-Vrhovac , D. Kubelka , B. Ivanic , T. Dabo , A. Mijić
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引用次数: 32

Abstract

The presence of structural chromosome aberrations and sister chromatid exchange frequencies (SCE) were studied in lymphocytes from 28 male subjects occupationally exposed to vinyl chloride monomer for a period of 9 years. A significant increase in chromosomal damages and elevated SCE frequencies was detected during the third and fourth year of the follow-up study. During the last 2 years, all examined parameters are approaching control values. This is a result of decreasing vinyl chloride monomer concentrations in the working environment without interrupting the working process.

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职业性氯乙烯单体暴露人群9年随访研究
本文研究了28名职业暴露于氯乙烯单体9年的男性受试者淋巴细胞中结构染色体畸变和姐妹染色单体交换频率(SCE)的存在。在第三和第四年的随访研究中,发现染色体损伤显著增加,SCE频率升高。在过去两年中,所有检查的参数都接近控制值。这是在不中断工作过程的情况下降低工作环境中氯乙烯单体浓度的结果。
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