Repeating hemorrhage with a long duration after radiotherapy for glioma: radiological and histological observations.

H Kawano, K Sato, K Hosotani, T Kubota, T Goya, S Arikawa, S Wakisaka
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Abstract

A case of radiation necrosis which was observed 6 years after radiotherapy for a glioma in the right parietal lobe is reported. This patient developed hemiparesis, and radiological examinations showed similar findings consisted with recurrent glioma. Histological examination disclosed the lesion to be radiation necrosis. Repeated episodes of hemorrhage and cystic formation in the right hemisphere appeared during 8 to 10 years after radiotherapy, and removal of the mass lesion conducted four times. Histological examinations of each specimen showed the increasing proliferation of neo-vessels accompanied by hemorrhage and cystic formation.

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胶质瘤放射治疗后长时间反复出血:影像学和组织学观察。
本文报告一例右顶叶胶质瘤放射治疗6年后发生放射性坏死的病例。该患者出现偏瘫,放射检查显示与复发性胶质瘤相似。组织学检查显示病变为放射性坏死。放疗后8 ~ 10年反复出现右半球出血和囊性形成,并进行了4次肿块切除。每个标本的组织学检查显示新生血管增生增加,并伴有出血和囊性形成。
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