{"title":"Sister chromatid exchange frequency in inhabitants exposed to asbestos in Turkey","authors":"Hamiyet Dönmez , Yusuf özkul , Ramazan Uçak","doi":"10.1016/S0165-1161(96)90247-2","DOIUrl":null,"url":null,"abstract":"<div><p>Pleural mesothelioma, lung cancer, pleural calcification and fibrosis have been observed among inhabitants of the villages in Ivriz-Zanapa valley in Turkey. Earlier reports have stated that these endemic pathological conditions are caused by the inhalation of actinolite asbestos, a mineral commonly used indiscriminately to paint the walls and floors of houses. In the present study, 40 inhabitants in Yassikaya village in Ivriz-Zanapa valley and 20 controls were further investigated. The peripheral blood lymphocytes were cultured and harvested at 72 h for sister chromatid exchange (SCE) frequency. Inhabitants had a raised mean SCE rate compared with a control population.</p></div>","PeriodicalId":18870,"journal":{"name":"Mutation Research\\/environmental Mutagenesis and Related Subjects","volume":"361 2","pages":"Pages 129-132"},"PeriodicalIF":0.0000,"publicationDate":"1996-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0165-1161(96)90247-2","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Mutation Research\\/environmental Mutagenesis and Related Subjects","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0165116196902472","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 12
Abstract
Pleural mesothelioma, lung cancer, pleural calcification and fibrosis have been observed among inhabitants of the villages in Ivriz-Zanapa valley in Turkey. Earlier reports have stated that these endemic pathological conditions are caused by the inhalation of actinolite asbestos, a mineral commonly used indiscriminately to paint the walls and floors of houses. In the present study, 40 inhabitants in Yassikaya village in Ivriz-Zanapa valley and 20 controls were further investigated. The peripheral blood lymphocytes were cultured and harvested at 72 h for sister chromatid exchange (SCE) frequency. Inhabitants had a raised mean SCE rate compared with a control population.
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