Actin-based organelle movement.

Experientia Pub Date : 1996-12-15 DOI:10.1007/BF01952110
V R Simon, L A Pon
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引用次数: 28

Abstract

Evidence for actin-dependent organelle movement was first obtained from studies of cytoplasmic streaming in plants. These studies, together with cell-free organelle motility studies and biophysical analyses of muscle myosin, support a model whereby organelle-associated motor molecules utilize the energy of adenosine triphosphate binding and hydrolysis to drive movement along F-actin tracks. Recent studies indicate that this mechanism for organelle movement may be responsible for organelle and vesicle movement during secretion, endocytosis and mitochondrial inheritance in a variety of eukaryotes.

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基于肌动蛋白的细胞器运动。
肌动蛋白依赖细胞器运动的证据最初是在植物细胞质流动的研究中获得的。这些研究,加上无细胞细胞器运动研究和肌球蛋白的生物物理分析,支持了一个模型,即细胞器相关运动分子利用三磷酸腺苷结合和水解的能量来驱动f -肌动蛋白轨迹的运动。最近的研究表明,这种细胞器运动机制可能与多种真核生物在分泌、内吞作用和线粒体遗传过程中的细胞器和囊泡运动有关。
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