1 What is early rheumatoid arthritis?: definition and diagnosis

MA, MD, FRCP Paul Emery (ARC Professor of Rheumatology, Consultant Rheumatologist) , MD, FRCP Deborah P.M. Symmons (Consultant Senior Lecturer, Consultant Rheumatologist)
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引用次数: 45

Abstract

The diagnosis of early rheumatoid arthritis (RA) has inherent difficulties. It requires assessment, not only of the current clinical picture, but of the potential for change. As the pathognomonic feature of RA, is persistence it is not surprising that the American College of Rheumatologists criteria perform better in predicting persistence than severity. An adequate histological/imaging method of diagnosing RA is awaited. In the interim, a pragmatic approach to defining disease has been suggested, which takes a homogeneous group of patients with persistent inflammatory small joint synovitis and secondarily stages them for severity. This proposal is currently being assessed for clinical usefulness.

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1什么是早期类风湿性关节炎?定义与诊断
早期类风湿关节炎(RA)的诊断有其固有的困难。它需要评估,不仅是目前的临床情况,而且是潜在的变化。由于类风湿关节炎的病理特征是持续性,因此美国风湿病学会的标准在预测持续性方面优于预测严重程度并不奇怪。一种适当的诊断RA的组织学/影像学方法正在等待中。在此期间,已经提出了一种实用的方法来定义疾病,该方法采用一组具有持续性炎症性小关节滑膜炎的同质患者,并根据严重程度对其进行二次分期。目前正在评估该建议的临床有效性。
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