Software for the analysis of DNA sequence elements of transcription.

Computer applications in the biosciences : CABIOS Pub Date : 1997-02-01 DOI:10.1093/bioinformatics/13.1.89

K Frech, K Quandt, T Werner

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引用次数: 47

Abstract

The detection of transcription control elements in DNA sequences became both more important and more complicated by the completion of the first full genome sequencing projects. Rapid evaluation of potential regulatory elements in large amounts of sequence data requires specific methods preferably available as user-friendly computer programs. However, many more algorithms and methods have been published than programs are available, creating problems for scientists who try to select an appropriate method for their needs from the literature. The Internet provides a worldwide and relatively easy access to computer software if the user knows where to look. One of the major problems remaining is how to find the appropriate software. We have compiled a guide detailing where software is available and what is to be expected in terms of interface and data compatibility with other programs. We also show results obtained with each program for several examples. The summarized features of each program should allow scientists to select quickly the method of their choice and inform them where to download the software.

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用于分析DNA序列转录元件的软件。

随着首个全基因组测序项目的完成，DNA序列中转录控制元件的检测变得更加重要和复杂。快速评估大量序列数据中潜在的调控元素需要特定的方法，最好是用户友好的计算机程序。然而，已经发表的算法和方法比可用的程序要多得多，这给试图从文献中选择适合自己需要的方法的科学家带来了问题。如果用户知道在哪里查找，互联网提供了一个全球范围内相对容易的访问计算机软件的途径。剩下的主要问题之一是如何找到合适的软件。我们编制了一份指南，详细说明了软件的可用位置，以及在接口和与其他程序的数据兼容性方面的期望。我们还通过几个例子展示了每个程序得到的结果。每个程序的总结特征应该允许科学家快速选择他们选择的方法，并告知他们在哪里下载软件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Computer applications in the biosciences : CABIOS

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