Incidence of bacterial colonization in the throat and in urines at paediatric age with evaluation of sensitivity to common antibiotics.

S Catania, M T Mascellino, C Ajassa, G Berardelli, R Bellagamba, S Tzanzoglou, F Iegri, M P Ronchetti, N Catania
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Abstract

Objectives: To evaluate the incidence of bacterial colonization in the throat and in urines of children admitted to a paediatric ward in the year 1994. To test the sensitivity of isolates on the most common antibiotics used in therapy.

Methods: The investigation was carried out on a group of 270 children (125 male and 145 female), aged between 3 months and 12 years, hospitalized with feverish infectious pathology in the department of infectious and Tropical Diseases of the University "La Sapienza" of Rome. The cultures of the throat swabs and on urines were performed on the admission of the children before the beginning of the therapy.

Results: The throat-swab cultures showed pathogenous microrganisms in 232 samples (85.9%) with a slight prevalence of Gram-negative bacteria (122) with respect to Gram-positive (110) and saprophytic microbial flora (38). The urine cultures proved to be positive in 81 cases (30%) with a prevalence of Gram-negative (56) above Gram-positive isolates (25).

Conclusions: The two/thirds of paediatric patients hospitalized in an Infectious Diseases Department appeared to be colonized in the upper respiratory tract, whereas in about 10% of them a marked bacteriuria was clearly evident, often in the absence of specific symptoms. A few isolates either from the throat or from urines, showed resistance to the common antibacterial agents.

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儿童期咽喉和尿液中细菌定植的发生率及对常见抗生素的敏感性评估。
目的:评价1994年某儿科病房收治的儿童咽喉和尿液中细菌定植的发生率。测试分离株对治疗中最常用抗生素的敏感性。方法:对罗马“La Sapienza”大学传染病和热带病科发热感染病理科住院的270例儿童(男125例,女145例)进行调查,年龄3个月~ 12岁。在治疗开始前,患儿入院时进行咽拭子和尿液培养。结果:痰拭子培养检出病原菌232例(85.9%),其中革兰氏阴性菌122例,革兰氏阳性菌110例,腐生菌38例。81例(30%)尿培养呈阳性,革兰氏阴性(56例)高于革兰氏阳性(25例)。结论:在某传染病科住院的儿童患者中,三分之二的患者出现上呼吸道定植,而其中约10%的患者在没有特定症状的情况下明显可见明显的细菌尿。从咽喉或尿液中分离出的少数菌株对常见的抗菌药物有耐药性。
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