Epidemic patterns and carriage of Chlamydia pneumoniae in Norway.

B P Berdal, O Scheel, G N Thomas, C M Black, N K Meidell
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Abstract

Chlamydia pneumoniae infection, in earlier days misdiagnosed as ornithosis, is very common in Norway. The disease develops slowly, a feature that may account for the very large number of subclinical cases, which may be seven fold more common than clinical cases. Subclinical cases produce an antibody response similar to that seen in overt clinical disease. Silent carriage of C. pneumoniae in healthy individuals may be frequent. Therapy based on positive cell culture or polymerase chain reaction (PCR) in the absence of pneumonic symptoms may be questionable. PCR has, however, given the slow development of disease, revealed itself as a handy epidemiological technique useful for the survey of healthy populations.

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挪威肺炎衣原体的流行模式和携带。
肺炎衣原体感染,在早期被误诊为鸟类病,在挪威很常见。这种疾病发展缓慢,这一特征可能是大量亚临床病例的原因,亚临床病例可能比临床病例多7倍。亚临床病例产生与显性临床疾病相似的抗体反应。在健康个体中,隐性携带肺炎原体可能是常见的。在没有肺炎症状的情况下,基于阳性细胞培养或聚合酶链反应(PCR)的治疗可能值得怀疑。然而,鉴于疾病发展缓慢,聚合酶链反应显示其本身是一种方便的流行病学技术,可用于健康人群的调查。
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