9 Surgery in portal hypertension

David A. Iannitti MD (Fellow in Pancreatic and Hepatobiliary Surgery) , J.Michael Henderson MD, Chb, FRCS, FACS (Chairman)
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引用次数: 8

Abstract

The role of surgery in portal hypertension remains a topic of debate. For the past 100 years, various surgical procedures have been used to treat variceal bleeding, refractory ascites, and end-stage liver disease. The past decade has seen significant advances in pharmacotherapy, endoscopy, interventional radiology, and surgery for the management of patients with portal hypertension. Liver transplantation has come of age in the 1990s and is now an accepted therapy for patients with end-stage liver disease. The wide array of management options can complicate the decision making process and defines the need to evaluate these patients fully. Factors such as the aetiology and extent of liver disease, response to prior medical, endoscopic, and other interventional treatments, and possibility of future liver transplantation must be considered. This manuscript will review the history of surgical treatments of portal hypertension, describe the surgical procedures with their advantages and disadvantages, and evaluate their role in the elective and emergent settings.

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门静脉高压症的外科治疗
手术在门静脉高压症中的作用仍然是一个有争议的话题。在过去的100年里,各种外科手术已被用于治疗静脉曲张出血、难治性腹水和终末期肝病。在过去的十年中,门静脉高压症患者的药物治疗、内窥镜检查、介入放射学和手术治疗取得了重大进展。肝移植在20世纪90年代已经成熟,现在是终末期肝病患者的一种公认的治疗方法。各种各样的管理选择可能使决策过程复杂化,并确定需要对这些患者进行全面评估。必须考虑肝病的病因和程度、对既往医学、内窥镜和其他介入治疗的反应以及未来肝移植的可能性等因素。本文将回顾门静脉高压手术治疗的历史,描述手术方法及其优缺点,并评估其在选择性和紧急情况下的作用。
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