[Open heart surgery in a Jehovah's Witness boy--a case report of successful management of aortic regurgatation and aneurysm of sinus Valsalva due to infective endocarditis].

Y Sawada, K Asada, N Matsuyama, S Hasegawa, S Sasaki
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Abstract

Jehovah's Witness who require operation represent a challenge to the physician because of the patients' refusal to accept blood transfusion. We report an 8-year-old male of Jehovah's Witness who underwent a surgical treatment of infective endocarditis. He was transferred to our hospital because of high fever and heart murmur. Echocardiogram revealed a developing vegetation of aortic cusps and an aneurysmal change of the non-coronary sinus Valsalva. On admission he was complicated by anemia, purulent meningitis and suppurative arthritis of left knee. There were no signs of cardiac failure. Erythropoietin (6000 U thrice weekly) and iron (60 mg daily) were given for 11 weeks prior to surgery, raising the hemoglobin level from 9.2 g/dl to 18.4 g/dl. Aortic valve replacement and plasty of the sinus Valsalva were then performed. Intraoperatively hemoglobin concentration dropped to 10.3 g/dl and it raised to 15 g/dl postoperatively. We also used Cell-Saver to reduce blood loss. The patient made an uncomplicated recovery. Erythropoietin therapy contributed substantially to the successful outcome of this case.

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[耶和华见证会男孩的心脏手术——一例成功治疗因感染性心内膜炎引起的主动脉反流和Valsalva窦动脉瘤的病例报告]。
需要手术的耶和华见证人对医生来说是一个挑战,因为病人拒绝接受输血。我们报告一位8岁的耶和华见证人男性,他接受了感染性心内膜炎的手术治疗。他因为高烧和心脏杂音被转到我们医院。超声心动图显示主动脉弓尖的生长和非冠状窦Valsalva的动脉瘤样改变。入院时并发贫血、化脓性脑膜炎和左膝化脓性关节炎。没有心脏衰竭的迹象。手术前11周给予促红细胞生成素(6000 U,每周3次)和铁(60 mg,每天),使血红蛋白水平从9.2 g/dl提高到18.4 g/dl。然后进行主动脉瓣置换术和Valsalva窦成形术。术中血红蛋白浓度降至10.3 g/dl,术后升高至15 g/dl。我们也用Cell-Saver来减少失血。病人恢复得很简单。促红细胞生成素治疗在很大程度上促成了这个病例的成功结果。
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