[Thoracoscopic resection of mediastinal parathyroid adenoma with cyst and hyperparathyroidism--a case report].

M Shimizu, H Akamatsu, T Yoshizaki, H Tanaka, T Sakamoto, M Sunamori
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Abstract

A 51-year-old woman was admitted because of general fatigue assumed to be due to climacteric disturbance. Laboratory examinations suggested a diagnosis of hyperparathyroidism based on high serum levels of Ca, intact PTH, and high-sensitivity PTH. No abnormalities were found in the cervix. Chest X-ray films and CT scans showed a mass measuring 4 cm in the right postero-upper mediastinum. The tumor was positive on a parathyroid scintigram, and was diagnosed as a mediastinal parathyroid adenoma with hyperparathyroidism. Operative findings showed a tumor surrounded by the superior vena cava, vagus nerve, azygos vein, and brachiocephalic artery. Careful resection of the hypervascular tumor from surrounding tissues was performed using a thoracoscopic technique alone. The postoperative course was uneventful. Serum values of Ca, intact PTH, and high-sensitivity PTH decreased to within normal ranges. after surgery. Pathohistological study confirmed the diagnosis of parathyroid adenoma including a cyst caused by degeneration of the tumor.

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[胸腔镜切除纵隔甲状旁腺瘤合并囊肿、甲状旁腺功能亢进1例]。
一名51岁妇女因全身疲劳被认为是由于更年期紊乱而入院。实验室检查建议诊断甲状旁腺功能亢进基于高血钙水平,完整的甲状旁腺素,和高敏感性甲状旁腺素。子宫颈未见异常。胸部x线片和CT扫描显示右侧后上纵隔有一个4厘米的肿块。肿瘤在甲状旁腺闪片上呈阳性,诊断为纵隔甲状旁腺瘤伴甲状旁腺功能亢进。手术结果显示肿瘤被上腔静脉、迷走神经、奇静脉和头臂动脉包围。仅使用胸腔镜技术从周围组织中仔细切除高血管肿瘤。术后过程平淡无奇。血清钙、完整甲状旁腺素和高敏甲状旁腺素降至正常范围。手术后。病理组织学研究证实了甲状旁腺瘤的诊断,包括由肿瘤变性引起的囊肿。
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