{"title":"Lack of effect of suprachiasmatic infusion of a vasopressin antagonist on the circadian rhythm of wheel-running activity in rats.","authors":"A G Stoynev, K Nagai","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Circadian patterns of wheel-running activity were studied in male Wistar rats before, during, and after continuous infusion of (Pmp1, Tyr(Me)2)-Arg8-vasopressin, a V1 receptor antagonist, in the suprachiasmatic region by means of Alzet mini-osmotic pumps. The lack of any significant effect on the pattern of wheel-running activity argues against a role for vasopressin in the generation of circadian rhythms by the suprachiasmatic nuclei.</p>","PeriodicalId":7035,"journal":{"name":"Acta physiologica et pharmacologica Bulgarica","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta physiologica et pharmacologica Bulgarica","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Circadian patterns of wheel-running activity were studied in male Wistar rats before, during, and after continuous infusion of (Pmp1, Tyr(Me)2)-Arg8-vasopressin, a V1 receptor antagonist, in the suprachiasmatic region by means of Alzet mini-osmotic pumps. The lack of any significant effect on the pattern of wheel-running activity argues against a role for vasopressin in the generation of circadian rhythms by the suprachiasmatic nuclei.
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