Avoidable cancers in the Nordic countries. External environment.

APMIS. Supplementum Pub Date : 1997-01-01
L Dreyer, A Andersen, E Pukkala
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Abstract

Air pollutants arising from traffic clustering and industrial production include a number of chemical compounds that at high doses are carcinogenic in animal models and in some instances also in humans. Direct epidemiological evidence for a carcinogenic effect of air pollution in humans is, however, weak, and most of the available studies are limited by lack of adequate control of confounding factors and other methodological drawbacks. Limited evidence exists for a link between urban air pollution and lung cancer, with reported relative risks of 1.0-1.5. About one-third of the population of the Nordic countries, corresponding to 7.3 million people, lives in urban areas. If there is an excess risk associated with air pollution, the annual number of lung cancer cases around the year 2000 in the Nordic countries would range from 0 (no excess risk) to 1,800 (relative risk, 1.5). As the existence of a causal link between air pollution and cancer is not uncorroborated, measures for avoiding cancer from this source cannot be recommended.

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北欧国家可避免的癌症。外部环境。
交通拥挤和工业生产产生的空气污染物包括许多化合物,在高剂量下对动物模型具有致癌性,在某些情况下也对人类具有致癌性。然而,关于空气污染对人类致癌作用的直接流行病学证据很薄弱,而且大多数现有的研究由于缺乏对混杂因素的适当控制和其他方法上的缺陷而受到限制。城市空气污染与肺癌之间存在联系的证据有限,报告的相对风险为1.0-1.5。北欧国家大约三分之一的人口,即730万人生活在城市地区。如果存在与空气污染有关的超额风险,北欧国家2000年前后每年的肺癌病例数将在0(无超额风险)至1800(相对风险,1.5)之间。由于空气污染与癌症之间的因果关系并非未经证实,因此不能建议采取措施避免从这一来源患上癌症。
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