Condylomata acuminata of the penis progressing rapidly to invasive squamous cell carcinoma.

Abstract

Introduction Condylomata acuminata are caused by human papilloma virus (HPV) infections and epidemiological and molecular-biological evidence points to an association between HPV infection and anogenital dysplasia.' Human immunodeficiency virus (HIV) infection has been implicated as a promoting factor.2 In Zimbabwe the National Cancer Registry reports cervical carcinoma as the most common malignancy and recently an increase in reported squamous cell carcinoma of the penis has been observed, from one case per annum in 1993 and 1994 to six cases in 1995 and five cases in 1996.3 I report here a patient with AIDS who rapidly developed squamous cell carcinoma of the penis in conjunction with longstanding condylomata acuminata.