An audit of pancreatic pseudocyst management and the role of endoscopic pancreatography.

B Ng, B Murray, G Hingston, J A Windsor
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Abstract

Background: A rational algorithm for the management of symptomatic pancreatic pseudocysts is necessary with the increasing availability of radiological, surgical and endoscopic methods of treatment.

Methods: A retrospective audit of the management and outcome of all patients who presented with symptomatic pancreatic pseudocysts to the Auckland Hospital over a 9-year period (1988-96) was made.

Results: There were 44 patients (28 men, 16 women; median age 50; range 18-81) in this series. Initial management was not based on pseudocyst size, duration, location, wall thickness, the patients' symptoms and comorbidity, or the aetiology of pancreatitis. Of the 27 patients who had initial conservative management, 15 pseudocysts (56%) completely resolved. Of the 17 patients who were initially or subsequently treated with percutaneous catheter drainage (PCD), 10 pseudocysts (59%) completely resolved without additional treatment. Of the 13 patients initially or subsequently treated by surgery, all but one completely resolved after the first procedure. Two patients were successfully treated with endoscopic pancreatic stent placement. Complications arose in eight patients treated with PCD (47%) and four patients treated with surgery (31%). There was no mortality. The decision for active treatment was not preceded by delineation of the pancreatic duct by ERCP (endoscopic retrograde cholangiopancreatography) in 60% of patients.

Conclusions: More than one-third of all patients with symptomatic pancreatic pseudocysts can be managed conservatively. Surgery yields excellent results but PCD has a high failure rate in patients with an underlying pancreatic duct stricture. A rational management algorithm is presented, based on pre-intervention ERCP, which should improve patient selection and outcome.

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胰脏假性囊肿的处理及内镜胰脏造影的作用。
背景:随着放射、手术和内窥镜治疗方法的增加,有症状的胰腺假性囊肿的合理治疗方法是必要的。方法:回顾性分析奥克兰医院9年间(1988- 1996年)所有出现症状性胰腺假性囊肿患者的治疗和预后。结果:44例患者(男28例,女16例;中位年龄50岁;范围18-81)。最初的治疗不是基于假性囊肿的大小,持续时间,位置,壁厚,患者的症状和合并症,或胰腺炎的病因。在27例初始保守治疗的患者中,15例假性囊肿(56%)完全消退。在最初或随后接受经皮导管引流(PCD)治疗的17例患者中,10例假性囊肿(59%)在没有额外治疗的情况下完全消退。在最初或随后接受手术治疗的13例患者中,除1例外,其余患者在第一次手术后完全消退。2例患者成功接受内镜下胰腺支架置入术。8例PCD患者(47%)和4例手术患者(31%)出现并发症。没有死亡。在决定积极治疗之前,60%的患者没有通过ERCP(内窥镜逆行胰胆管造影)划定胰管。结论:超过三分之一的症状性胰腺假性囊肿患者可以保守治疗。手术治疗效果良好,但PCD在胰管狭窄的患者中失败率很高。提出了一种基于干预前ERCP的合理管理算法,可改善患者选择和预后。
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