Stress fiber networks in sinus endothelial cells in the rat spleen.

IF 2.1 4区 医学 Q2 Agricultural and Biological Sciences Anatomical Record Pub Date : 1999-01-01 DOI:10.1002/(SICI)1097-0185(19990101)254:1<22::AID-AR4>3.0.CO;2-#
K Uehara, M Miyoshi
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引用次数: 7

Abstract

The wall of the splenic sinus is well known to be a critical site in the control of the blood‐cell passage through the splenic cord. However, there is little information on what mechanism controls the blood‐cell passage between the sinus endothelial cells adhered with intercellular junctions.
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大鼠脾窦内皮细胞的应激纤维网络。
众所周知,脾窦壁是控制血细胞通过脾索的关键部位。然而,关于细胞间连接处黏附的窦内皮细胞间的血细胞通道控制机制的信息很少。采用透射电镜和免疫荧光显微镜观察大鼠脾窦内皮细胞的应力纤维。经皂苷提取后,发现应力纤维在细胞基部具有明显的电子密度,并表现出两种特征类型和混合类型。一种类型的应力纤维呈波纹状,形成厚的电子密集束,另一种类型的应力纤维呈直线束,间隔有电子密集区。统计上,两种应力纤维的长度有显著差异。虽然大多数应力纤维被环状纤维分割,但也有一些应力纤维先后跑出环状纤维的附着部位,从而在细胞基部纵向和切向拉伸,形成广泛的网络。神经网络的外周分别在环纤维处与基膜相连,在局灶黏附和细胞-细胞黏附连接处与侧膜相连。磷酸酪氨酸位于内皮细胞的基底部和细胞间粘附部位。两种应力纤维在窦内皮细胞内组织,形成广泛的网络。应力纤维可能在信号转导和细胞附着与脱离的调控中起重要作用。
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来源期刊
Anatomical Record
Anatomical Record Agricultural and Biological Sciences-Ecology, Evolution, Behavior and Systematics
CiteScore
4.30
自引率
0.00%
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0
期刊介绍: The Anatomical Record
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