Neonatal and maternal levels of lipid-soluble antioxidants.

L Iughetti, E Maggi, C Volta, G Palladini, G Bellomo, S Bernasconi
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Abstract

Lipid peroxidation plays an important role in the pathogenesis of several neonatal complications. To improve the knowledge on the antioxidant lipid-soluble defenses in neonatal age, we investigated a group of healthy full-term infants and their mothers measuring by high-pressure liquid chromatography the levels of vitamin E and carotenoids. Our data demonstrate that neonatal levels of lipid-soluble anti-oxidants are lower than the maternal ones. Moreover we show that neonatal Vitamin E and carotenoid concentrations are respectively unrelated and strictly related to maternal levels of the same lipid-soluble anti-oxidants.

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新生儿和母亲的脂溶性抗氧化剂水平。
脂质过氧化在几种新生儿并发症的发病机制中起重要作用。为了提高对新生儿年龄抗氧化脂溶性防御的认识,我们调查了一组健康的足月婴儿及其母亲,用高压液相色谱法测量了维生素E和类胡萝卜素的水平。我们的数据表明,新生儿的脂溶性抗氧化剂水平低于母亲。此外,我们表明新生儿维生素E和类胡萝卜素浓度分别与母体相同的脂溶性抗氧化剂水平无关,并严格相关。
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