Evaluation of behavioral and social issues among Thai HIV vaccine trial volunteers.

Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association Pub Date : 1999-03-01 DOI:10.1097/00042560-199903010-00015

D Thapinta, R A Jenkins, D D Celentano, S Nitayaphan, P Buapunth, A Triampon, P A Morgan, C Khamboonruang, C Suwanarach, Y Yutabootr, S Ruckphaopunt, S Suwankiti, V Tubtong, W Cheewawat, J G McNeil, R A Michael

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引用次数: 33

Abstract

Behavioral and social issues were investigated in phase I/II preventive HIV vaccine trial volunteers in Thailand. These included risk behavior, HIV knowledge, distress, and social experiences associated with trial participation. Data were collected at baseline and at 4- and 8-month follow-up visits. Volunteers reported relatively low levels of risk behaviors at baseline and at the follow-up visits. About one fifth reported overtly negative reactions from family or friends. No problems with discrimination in employment, health care, or insurance were reported. Findings add to the evidence suggesting the feasibility of phase I/II prophylactic HIV vaccine trials with low-risk volunteers in Thailand.

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评估泰国HIV疫苗试验志愿者的行为和社会问题。

对泰国预防性艾滋病毒疫苗第一/二期试验志愿者的行为和社会问题进行了调查。这些因素包括风险行为、艾滋病知识、痛苦和与参与试验相关的社会经历。在基线和4个月和8个月的随访中收集数据。志愿者在基线和随访时报告的危险行为水平相对较低。大约五分之一的人报告了来自家人或朋友的公开负面反应。没有报告在就业、保健或保险方面存在歧视问题。研究结果进一步证明了在泰国开展低风险志愿者预防性艾滋病毒疫苗I/II期试验的可行性。

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Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association

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