6 Short bowel syndrome

Bailliere's clinical gastroenterology Pub Date : 1998-12-01 DOI:10.1016/S0950-3528(98)90006-9

I.W. Booth BSc, MSc, MD, FRCP, FRCPCH, DObstRCOG, DCH (Leonard Parsons Professor of Paediatrics and Child Health Honorary Consultant in Paediatric Gastroenterology and Nutrition), A.D. Lander PhD FRCS(Paed) DCH (Senior Lecturer in Paediatric Surgery Honorary Consultant in Paediatric Surgery)

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引用次数: 42

Abstract

Short bowel syndrome has significant morbidity and is potentially lethal especially when intestinal loss is extensive. The pathophysiology of short bowel syndrome, its aetiology, prognosis and our understanding of the mechanisms of adaptation are reviewed. Management by a multi-disciplinary nutritional care team is advocated and should be directed to the maintenance of growth and development, the promotion of intestinal adaptation, the prevention of complications and the establishment of enteral nutrition. The choice of enteral feed, the role of drugs and the use of pro-adaptive nutrients and agents are discussed. Complications including cholestasis and catheter related sepsis are outlined with strategies to reduce them. Finally the roles of secondary surgical interventions including transplantation are discussed.

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6短肠综合征

短肠综合征具有显著的发病率，特别是当肠道大面积丧失时，具有潜在的致命性。本文综述了短肠综合征的病理生理、病因、预后以及我们对适应机制的认识。提倡由多学科营养护理团队进行管理，并应针对维持生长发育，促进肠道适应，预防并发症和建立肠内营养。讨论了肠内饲料的选择、药物的作用以及促适应营养物质和制剂的使用。并发症包括胆汁淤积和导管相关败血症概述了策略，以减少他们。最后讨论了包括移植在内的二次手术干预的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Bailliere's clinical gastroenterology

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