Towards the safer use of warfarin II: Results of a workshop

PJ Halstead BPharm, MPS, EE Roughead BPharm, MAppSc, K Rigby RN, BEc, MSc(Med), MSc(Hlth Econ), RB Clark BSc, MPH, AS Gallus MB BS, FRCPA, FRACP, FRCP(C)
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引用次数: 9

Abstract The use of oral anticoagulation therapy (ACT) is expanding. Due to the combination of the narrow therapeutic range and relatively unpredictable pharmacokinetics and pharmacodynamics, there are relatively high risks involved in using this treatment. The purpose of this paper is to present the results of a focus group’s canvassing of ways to improve the management of the use of oral anticoagulants. Recommendations proposed include: (i) better patient selection; (ii) more patient involvement and research into the appropriateness of the current use of ACT in Australia; (iii) increased production, dissemination and implementation of ACT guidelines; (iv) assessment of home and practice ACT monitoring; and (v) research into the effectiveness of academic detailing and the use of management plans by dedicated ACT educators.

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迈向华法林的安全使用II:研讨会的结果
口服抗凝治疗(ACT)的应用正在扩大。由于治疗范围窄,药代动力学和药效学相对不可预测,因此使用该治疗具有较高的风险。本文的目的是介绍焦点小组对改善口服抗凝剂使用管理的方法的调查结果。建议包括:(i)更好地选择患者;(ii)对澳大利亚目前使用ACT的适当性进行更多的患者参与和研究;(iii)加强对acts准则的编制、传播和实施;(iv)评估家庭和实践ACT监测;(v)由专门的ACT教育工作者对学术细节和管理计划使用的有效性进行研究。
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