Diagnostic applications of repetitive DNA sequences.

J T Epplen
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Abstract

Different diagnostic applications are discussed for various categories of repetitive DNA sequences. Since all eukaryotes are characterized by genomic redundancy, these sensitive, rapid, and comparatively simple techniques are revolutionizing many fields in clinical and experimental diagnostics. In addition to individuality testing in humans and animals, for example, eukaryotic infectious agents can be identified and tumors classified with respect to genomic changes. The forensic as well as animal and plant breeding sciences have already adopted the DNA technology involving repetitive sequence tools.

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重复DNA序列的诊断应用。
不同的诊断应用讨论了不同类别的重复DNA序列。由于所有真核生物都具有基因组冗余的特征,这些敏感、快速和相对简单的技术正在彻底改变临床和实验诊断的许多领域。例如,除了对人类和动物进行个别性检测外,还可以识别真核感染原,并根据基因组变化对肿瘤进行分类。法医和动植物育种科学已经采用了包含重复序列工具的DNA技术。
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