Is it possible to predict the efficacy at discharge of inhospital rheumatology department management of disk-related sciatica? A study in 150 patients.

Revue du rhumatisme (English ed.) Pub Date : 1999-04-01
J M Berthelot, D Rodet, P Guillot, Y Laborie, Y Maugars, A Prost
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Abstract

Objectives: To identify criteria for predicting the outcome at discharge in patients scheduled for inhospital treatment of disk-related sciatica.

Patients and methods: We studied 150 rheumatology department patients admitted for disk-related sciatica with a mean duration of 88 +/- 127 days to determine the impact on treatment outcomes of 50 parameters.

Results: After complete bed and 2.2 +/- 1.1 epidural glucocorticoid injections during a mean hospital stay of 9.9 +/- 4.3 days, 80% of patients reported either complete or partial pain relief (19% and 61%, respectively). The remaining 20% reported little (9%) or no (11%) change. Surgery was performed in 13% of cases. A tighter straight-leg raising test angle was correlated with treatment failure (P = 0.01). Complete bed rest duration prior to admission was shorter in the 80% of responders (P = 0.036) than in the 20% of nonresponders; in the overall population, patients spent on average 64% +/- 33% of daytime hours in bed. Patient predictions about their own outcomes were unreliable (P = 0.926). Patients who believed strongly that sciatica requires surgical treatment were more likely to be nonresponders (P = 0.06), as were patients with a family history of surgically-treated sciatica (P = 0.055). Outcomes were not correlated with any of the other parameters studied, including sciatica duration (P = 0.13), bedrest duration prior to admission (P = 0.52; mean duration, 18 +/- 29 days), the specialty of the physicians seen, investigations done prior to admission, or a history of sciatica (noted in 65% of cases and treated surgically in 16%).

Conclusions: Eighty percent of patients benefited from their hospital stay. Patient opinions on the merits of nonsurgical and surgical treatments in their own case were not correlated with their own outcomes. A tight straight leg-raising test angle was correlated with a poorer outcome. Neither sciatica duration nor rest duration prior to admission had an influence on outcome. Absence of complete bed rest prior to admission was correlated with a greater likelihood of a therapeutic benefit from the hospital stay.

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是否有可能预测住院风湿科治疗椎间盘相关性坐骨神经痛出院时的疗效?一项针对150名患者的研究。
目的:确定预测住院治疗椎间盘相关性坐骨神经痛患者出院预后的标准。患者和方法:我们研究了150例因椎间盘相关性坐骨神经痛入院的风湿科患者,平均持续时间为88±127天,以确定50个参数对治疗结果的影响。结果:在平均住院时间9.9 +/- 4.3天的完全卧床和2.2 +/- 1.1次硬膜外糖皮质激素注射后,80%的患者报告完全或部分疼痛缓解(分别为19%和61%)。剩下的20%报告变化很小(9%)或没有变化(11%)。13%的病例接受手术治疗。直腿抬高试验角度过紧与治疗失败相关(P = 0.01)。80%有反应的患者入院前完全卧床休息时间比20%无反应的患者短(P = 0.036);在总体人群中,患者平均有64% +/- 33%的白天时间在床上度过。患者对自身预后的预测不可靠(P = 0.926)。坚信坐骨神经痛需要手术治疗的患者更有可能无反应(P = 0.06),有手术治疗坐骨神经痛家族史的患者也是如此(P = 0.055)。结果与研究的任何其他参数无关,包括坐骨神经痛持续时间(P = 0.13),入院前卧床时间(P = 0.52;平均持续时间18±29天),就诊医师的专业,入院前的检查,或坐骨神经痛史(65%的病例注意到,16%的病例手术治疗)。结论:80%的患者在住院期间受益。患者对非手术和手术治疗优点的意见与他们自己的结果无关。抬高直腿的测试角度过紧与较差的结果相关。入院前坐骨神经痛持续时间和休息时间对结果均无影响。入院前没有完全卧床休息与住院治疗获益的可能性较大相关。
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