11 Phytoestrogen content in foods

MD Witold Mazur (Research Fellow)
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引用次数: 281

Abstract

Plants abound in essential phytochemicals produced for their various vital functions. The same compounds seem also to be crucial for human health and disease. Recent human epidemiological and laboratory animal and cell studies on cancer and heart disease have highlighted the phytoestrogens—naturally occurring principles that share with steroidal oestrogens an ability to activate oestrogen receptors. The best known non-steroidal phytoestrogens include the isoflavones daidzein, genistein, formononetin and biochanin A, the coumestan coumestrol, and the lignans secoisolariciresinol and matairesinol. Acknowledging the potentially chemoprotective role of these non-nutrients, we have quantified all biologically important isoflavonoids and lignans in cereals, oilseeds and nuts, legumes, vegetables, fruits, berries and beverages such as tea, coffee and wine. In this chapter, we present a review of our studies on staple plant foods, indicating that plants contain, besides a wide range of chemicals with a number of biological properties, biologically active phytoestrogens—precursors of hormone-like compounds found in mammalian systems.

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11食物中的植物雌激素含量
植物因其各种重要功能而产生大量必需的植物化学物质。这些化合物似乎对人类健康和疾病也至关重要。最近关于癌症和心脏病的人类流行病学、实验动物和细胞研究强调了植物雌激素——自然产生的原理,与甾体雌激素具有激活雌激素受体的能力。最著名的非甾体植物雌激素包括异黄酮大豆苷元、染料木素、刺芒柄花素和生物茶素A、coumestan coumestrol和木脂素第二异脂树脂醇和matmatresinol。认识到这些非营养素潜在的化学保护作用,我们量化了谷物、油籽和坚果、豆类、蔬菜、水果、浆果和饮料(如茶、咖啡和葡萄酒)中所有具有重要生物学意义的异黄酮和木脂素。在这一章中,我们回顾了我们对主要植物性食物的研究,表明植物除了含有一系列具有许多生物学特性的化学物质外,还含有具有生物活性的植物雌激素——哺乳动物系统中发现的激素样化合物的前体。
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