S Augy-Dorey, D C Billington, J A Camara, S D Gero, I Sagnard, B Quiclet-Sire, D Ghezzi
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引用次数: 0
Abstract
We have synthesised a number of analogues of lipid X, a precursor in the biosynthesis of LPS, some of which exhibit marked antagonism of LPS induced TNF production in vivo. These compounds provide new non-polar leads in the search for a therapy for endotoxic shock.
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