[The benefit of a coronary stent in the reduction of major cardiac complications in acute coronary syndromes].

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Abstract

To assess the incidence of in-hospital major adverse cardiac events (MACE), we analyzed 694 procedures in 613 consecutive patients during one year period. Patient population included 550 (79.2%) patients with unstable angina, 43 (6.2%) with stable angina and 101 (14.5%) with acute myocardial infarction. Elective percutaneous transluminal coronary angioplasty (PTCA) was performed in 593 (85.4%) patients, rescue PTCA in 7 (1%), and primary PTCA in 94 (13.5%). Angiographic lesion morphology was as follows: type A 30%; type B 58%; type C 12%. We compared patient population who received stent with PTCA-balloon only. Technical success was 95% and clinical success was achieved in 80% of the cases. Overall mortality was 1% in the stent group and 3% in the conventional PTCA. The incidence of MACE was 4% and 15.1% in the stent and angioplasty balloon groups respectively. We found a dramatic impact on reduction of the incidence of acute complications in the groups with stenting for unstable angina (p = 0.0001) and acute myocardial infarction (p = 0.0001). The major clinical advantage of stenting over balloon angioplasty was a lower need for repeated procedures.

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[冠状动脉支架在减少急性冠状动脉综合征的主要心脏并发症中的益处]。
为了评估院内主要心脏不良事件(MACE)的发生率,我们分析了613例连续患者一年内的694例手术。其中不稳定型心绞痛550例(79.2%),稳定型心绞痛43例(6.2%),急性心肌梗死101例(14.5%)。593例(85.4%)患者行择期经皮腔内冠状动脉成形术(PTCA),救救性PTCA 7例(1%),原发性PTCA 94例(13.5%)。血管造影病变形态如下:A型占30%;B型58%;C型12%。我们比较了接受支架和ptca球囊的患者。技术成功率为95%,临床成功率为80%。支架组的总死亡率为1%,传统PTCA组的总死亡率为3%。支架组MACE发生率为4%,球囊组MACE发生率为15.1%。我们发现支架置入治疗不稳定心绞痛组(p = 0.0001)和急性心肌梗死组(p = 0.0001)对降低急性并发症发生率有显著影响。与球囊血管成形术相比,支架置入术的主要临床优势是不需要重复手术。
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