A simple means of increasing muscle size after spinal cord injury: a pilot study.

G A Dudley, M J Castro, S Rogers, D F Apple
{"title":"A simple means of increasing muscle size after spinal cord injury: a pilot study.","authors":"G A Dudley,&nbsp;M J Castro,&nbsp;S Rogers,&nbsp;D F Apple","doi":"10.1007/s004210050609","DOIUrl":null,"url":null,"abstract":"<p><p>This study tested that hypothesis that skeletal muscle within a year of spinal cord injury (SCI) would respond to intermittent high force loading by showing an increase in size. Three males about 46 weeks post clinically complete SCI underwent surface electrical stimulation of their left or right m. quadriceps femoris 2 days per week for 8 weeks to evoke 4 sets of ten isometric or dynamic actions each session. Conditioning increased average cross-sectional area of m. quadriceps femoris, assessed by magnetic resonance imaging, by 20+/-1% (p = 0.0103). This reversed 48 weeks of atrophy such that m. quadriceps femoris 54 weeks after SCI was the same size as when the patients were first studied 6 weeks after injury. The results suggest that skeletal muscle is remarkably responsive to intermittent, high force loading after almost one year of little if any contractile activity.</p>","PeriodicalId":11936,"journal":{"name":"European Journal of Applied Physiology and Occupational Physiology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1999-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s004210050609","citationCount":"128","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Applied Physiology and Occupational Physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s004210050609","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 128

Abstract

This study tested that hypothesis that skeletal muscle within a year of spinal cord injury (SCI) would respond to intermittent high force loading by showing an increase in size. Three males about 46 weeks post clinically complete SCI underwent surface electrical stimulation of their left or right m. quadriceps femoris 2 days per week for 8 weeks to evoke 4 sets of ten isometric or dynamic actions each session. Conditioning increased average cross-sectional area of m. quadriceps femoris, assessed by magnetic resonance imaging, by 20+/-1% (p = 0.0103). This reversed 48 weeks of atrophy such that m. quadriceps femoris 54 weeks after SCI was the same size as when the patients were first studied 6 weeks after injury. The results suggest that skeletal muscle is remarkably responsive to intermittent, high force loading after almost one year of little if any contractile activity.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
增加脊髓损伤后肌肉大小的简单方法:一项初步研究。
这项研究验证了一种假设,即在脊髓损伤(SCI)一年内,骨骼肌会对间歇性高强度负荷做出反应,表现为大小增加。三名男性在临床完全性脊髓损伤后约46周,接受左股四头肌或右股四头肌表面电刺激,每周2天,持续8周,每组4组,每次10次等长或动态动作。经磁共振成像评估,预处理使股四头肌的平均截面积增加了20+/-1% (p = 0.0103)。这逆转了48周的萎缩,使脊髓损伤后54周的股四头肌大小与患者受伤后6周首次研究时相同。结果表明,骨骼肌在几乎一年没有任何收缩活动后,对间歇性的高强度负荷有明显的反应。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Acknowledgement to referees Acknowledgement to referees Acknowledgement to referees Acknowledgement to referees In vivo vibrational wave propagation in human tibiae at different ages
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1