Elimination of non-ionic contrast medium by hemodialysis in patients with impaired renal function.

Nihon Ika Daigaku zasshi Pub Date : 1999-10-01 DOI:10.1272/jnms.66.305

K Horiuchi, K Yoshida, N Tsuboi, M Akimoto, H Tajima, T Kumazaki

引用次数: 4

Abstract

The elimination rate of iohexol, a non-ionic contrast medium, from the blood by hemodialysis, and the elimination rate of iohexol by a dialyzer were studied in 15 patients with chronic renal dysfunction who required angiography or enhanced CT. The elimination rate of iohexol was 19.8% at 15 min after the start of hemodialysis, 30.6% after 30 min, 44.2% after 1 hour, 62.1% after 2 hours and 72.9% after 3 hours. The dialyzer elimination rate was maintained at about 75% from 1 to 3 hours after the start of hemodialysis. If only about 70% of iohexol in the blood needs to be eliminated, hemodialysis for 3 hours with a blood flow rate of 120 ml/min and a dialysate flow of 500 ml/min using a 0.7 m2 cellulose triacetate membrane is sufficient.

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肾功能受损患者血液透析消除非离子造影剂的作用。

本文对15例慢性肾功能不全患者进行血管造影或增强CT检查，观察血液透析对碘己醇(一种非离子造影剂)的清除率和透析对碘己醇的清除率。血液透析开始后15 min、30 min、1 h、2 h、3 h、62.1%对碘醇的清除率分别为19.8%、30.6%、44.2%、72.9%。血液透析开始后1 ~ 3小时，透析清除率维持在75%左右。如果只需要消除血液中约70%的碘己醇，则使用0.7 m2的三醋酸纤维素膜，以120 ml/min的血流量和500 ml/min的透析液进行3小时的血液透析就足够了。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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