[A case of systemic lupus erythematosus discovered from left heart failure due to lupus induced mitral regurgitation].

Ryumachi. [Rheumatism] Pub Date : 1999-10-01
K Ueno, S Fujimoto, T Fujimoto, H Nakano, T Nakajima, S Yamano, H Shiiki, T Hashimoto, K Imoto, S Miyagawa, K Dohi
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Abstract

A 50-year-old female was admitted to a local hospital because of dyspnea, and diagnosed as having left heart failure secondary to mitral regurgitation. After the improvement of congestive heart failure, polyarthralgia, fever, and positive anti-nuclear antibody were pointed out. She was referred to our hospital for the further evaluation. Serological test showed anti-double stranded DNA antibodies, anti-SS-A antibodies, anti-beta 2-GPI antibodies and biological false positive for syphilis. The diagnosis of SLE has been made from the clinical signs and the serology. Therefore mitral valvular lesion of this patient was considered to be one of the symptoms of SLE. We reported a rare case in which left heart failure was a initial clinical manifestation of SLE.

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[狼疮致二尖瓣反流左心衰竭并发系统性红斑狼疮1例]。
一名50岁女性因呼吸困难住进当地医院,诊断为二尖瓣返流引起的左心衰。充血性心力衰竭好转后出现多关节痛、发热、抗核抗体阳性。她被转介到我们医院做进一步的评估。血清学检测显示抗双链DNA抗体、抗ss - a抗体、抗β 2-GPI抗体,梅毒生物学假阳性。SLE的诊断主要是根据临床体征和血清学指标。因此,该患者的二尖瓣病变被认为是SLE的症状之一。我们报告了一例罕见的左心衰竭是SLE的初始临床表现。
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