Use of polyethylene glycol solution in functional and organic constipation in children.

A Staiano
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Abstract

A brief review is made of the use of high dose polyethylene glycol solution in the treatment of functional constipation and encopresis in children. Experience with low dose polyethylene glycol for the treatment of neurogenic constipation in children with severe brain damage is also reported. Treatment with polyethylene glycol caused a significant increase in bowel frequency and a decrease in gastrointestinal transit time. Side-effects, consisting of nausea, vomiting and irritability, have limited the use of this treatment in a few children.

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聚乙二醇溶液在儿童功能性和器质性便秘中的应用。
现就大剂量聚乙二醇溶液治疗儿童功能性便秘和膀胱积水的研究进展作一综述。低剂量聚乙二醇治疗严重脑损伤儿童神经源性便秘的经验也有报道。聚乙二醇治疗导致排便频率显著增加,胃肠道转运时间显著缩短。副作用,包括恶心、呕吐和易怒,限制了这种治疗在少数儿童中的应用。
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