Basic research in endoscopy.

R A Kozarek
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Abstract

Endoscopic research includes Technologic Development, Facilitated Research in which endoscopy may simply be a means to an end (such as to gauge a response to a pharmacologic agent or obtain tissue which is used for genetic analysis); Translational Research which can be defined as the clinical evaluation of endoscopic techniques or technology as well as the delivery of basic science innovations to patients endoscopically; and Outcomes Research. Defining the barriers to endoscopic research is much more important than the distinction of whether the research is basic or clinical. These barriers are multifactorial and include inadequate infrastructure and training and lack of both funding and protected time at the divisional level. Governmental, GI Societal, and industry financial support will all be required as will training programme revisions. The latter may include training in areas such as outcomes, physics, or biomedical engineering; and should also entail a formal mentoring process, "seed money" early in the investigator's career and protected time.

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内窥镜的基础研究。
内窥镜研究包括技术开发、便利研究,其中内窥镜检查可能只是达到目的的一种手段(例如衡量对药物的反应或获得用于遗传分析的组织);转化研究可以定义为内窥镜技术或技术的临床评估,以及内窥镜下向患者提供基础科学创新;和结果研究。界定内窥镜研究的障碍比区分研究是基础研究还是临床研究重要得多。这些障碍是多方面的,包括基础设施和培训不足以及在司一级缺乏资金和受保护的时间。政府、GI社会和行业的财政支持以及培训方案的修订都是必需的。后者可能包括结果、物理或生物医学工程等领域的培训;还应该包括一个正式的指导过程,在研究者职业生涯的早期提供“种子资金”和受保护的时间。
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