Arginase and ornithine, as markers in human non-small cell lung carcinoma.

Cancer biochemistry biophysics Pub Date : 1999-07-01
S Süer Gökmen, Y Yörük, E Cakir, F Yorulmaz, S Gülen
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Abstract

The arginase activity and ornithine level were determined in tissue obtained from patients with non-small cell lung carcinoma (NSLC). The arginase activity and ornithine level in tumor tissues were 1.89 +/- 1.28 U/mg protein and 42.32 +/- 25.82 nmol/mg protein, respectively versus 0.67 +/- 0.19 U/mg protein and 10.12 +/- 3.69 nmol/mg protein for normal tissues (p < 0.01).

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精氨酸酶和鸟氨酸作为人类非小细胞肺癌的标志物。
测定了非小细胞肺癌(NSLC)患者组织中精氨酸酶活性和鸟氨酸水平。肿瘤组织精氨酸酶活性为1.89 +/- 1.28 U/mg蛋白,鸟氨酸水平为42.32 +/- 25.82 nmol/mg蛋白,而正常组织精氨酸酶活性为0.67 +/- 0.19 U/mg蛋白,鸟氨酸水平为10.12 +/- 3.69 nmol/mg蛋白(p < 0.01)。
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