Endovascular repair of thoracic aortic aneurysms.

F Cartes-Zumelzu, J Lammer, G Kretschmer, T Hoelzenbein, M Grabenwöger, S Thurnher
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Abstract

The standard technique for the treatment of descending thoracic aortic aneurysms is elective open surgical repair with graft interposition. This standard approach, although steadily improving, is associated with high morbidity and substantial mortality rates and implies a major surgical procedure with lateral thoracotomy, use of cardiopulmonary bypass, long operation times and a variety of peri- and postoperative complications. This and the success of the first endoluminal treatment of abdominal aortic aneurysms by Parodi et al. prompted the attention to be thrown on the treatment of descending thoracic aortic aneurysms with endoluminal stent-grafts in many large centres. The aim of this new minimally invasive technique is to exclude the aneurysm from blood flow and in consequence to avoid pressure stress on the aneurysmatic aortic wall, by avoiding a large open operation with significant perioperative morbidity. The potentially beneficial effect of this new treatment approach was evaluated in the course of this study.

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胸主动脉瘤的血管内修复。
治疗胸降主动脉瘤的标准技术是选择性开放手术修复和移植物介入。这一标准方法虽然在稳步改进,但与高发病率和高死亡率相关,并且意味着需要进行外侧开胸手术、使用体外循环、手术时间长以及各种围手术期和术后并发症。这一发现以及Parodi等人首次在腔内治疗腹主动脉瘤的成功,促使许多大型中心开始关注腔内支架移植治疗胸降主动脉瘤。这种新的微创技术的目的是通过避免大的开放手术和明显的围手术期发病率,使动脉瘤从血液流动中排除,从而避免对动脉瘤主动脉壁施加压力。在本研究过程中评估了这种新治疗方法的潜在有益效果。
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