M A Golubev, V K Gorodetskiĭ, A P Anis'kina, A I Tochilkin, N F Beliaeva
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引用次数: 0
Abstract
The serum glucose concentration, HbAc1, fructoseamine, the activity of AST, ALT, amylase, glycogen content and glucokinase activity in rat hepatocytes were examined in streptozotocin-diabetic rats during long-term orthovanadate and vanadyl sulphate treatment. The improvement of this parameters were demonstrated after oral orthovanadate and vanadyl sulphate administration. However, insulin-mimetic properties of vanadyl sulphate were more marked in comparison with orthovanadate. LD-50 and cytotoxicity analysis in isolated hepatocytes showed that vanadyl sulphate was less toxic than orthovanadate.
Samuel Kyei, Rexford Kwasi Gyaami, John Baptist Abowine, Ebenezer Zaabaar, Augustine Nti, Kofi Asiedu, Samuel Bert Boadi-Kusi, Bismark Owusu-Afriyie, Frank Assiamah, Anthony Armah
S. Kyei, Rexford Kwasi Gyaami, John Baptist Vianney Abowine, Ebenezer Zaabaar, Augustine Nti, Kofi Fred Asiedu, S. Boadi-Kusi, Bismark Owusu-Afriyie, Frank Assiamah, Anthony Armah
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