E R Lemmer, J L Welch, T Tsai, C L Keck-Waggoner, C Huh, D B Zimonjic, N C Popescu, S S Thorgeirsson
{"title":"Genomic structure and chromosome location of the mouse RelA p65 gene (Rela).","authors":"E R Lemmer, J L Welch, T Tsai, C L Keck-Waggoner, C Huh, D B Zimonjic, N C Popescu, S S Thorgeirsson","doi":"10.1159/000015591","DOIUrl":null,"url":null,"abstract":"<p><p>The RelA (p65) subunit of transcription factor NF-kappaB plays a critical role in development, and rela(-/-) knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the genomic structure of mouse Rela and promoter, and have mapped the gene to chromosome 19B1-3.</p>","PeriodicalId":10982,"journal":{"name":"Cytogenetics and cell genetics","volume":"89 1-2","pages":"129-32"},"PeriodicalIF":0.0000,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000015591","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cytogenetics and cell genetics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000015591","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
The RelA (p65) subunit of transcription factor NF-kappaB plays a critical role in development, and rela(-/-) knockout mice die in utero from massive liver apoptosis. Only partial sequences of the mouse Rela gene are available. We have determined the genomic structure of mouse Rela and promoter, and have mapped the gene to chromosome 19B1-3.
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