A comparison of the efficacy and safety of morphine and pethidine as analgesia for suspected renal colic in the emergency setting.

A O'Connor, S A Schug, H Cardwell
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引用次数: 49

Abstract

Objectives: The aim of this study was to compare morphine and pethidine in patients with clinically suspected renal colic with regard to analgesic efficacy, patient satisfaction and side effects.

Methods: double blinded, randomised controlled trial.

Results: There was no significant difference between morphine and pethidine with respect to any of the parameters measured.

Conclusion: Because of the well known adverse effects that may be associated with pethidine use, the authors recommend that morphine should be the preferred agent in suspected renal colic, when an opioid analgesic is to be used.

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吗啡与哌替啶用于疑似肾绞痛急诊镇痛的疗效和安全性比较。
目的:本研究的目的是比较吗啡和哌替啶在临床疑似肾绞痛患者的镇痛效果、患者满意度和副作用。方法:双盲、随机对照试验。结果:吗啡与哌替啶在各项指标上均无显著性差异。结论:由于哌啶的不良反应可能与哌啶的使用有关,作者建议在使用阿片类镇痛药时,吗啡应作为疑似肾绞痛的首选药物。
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