Melvin Cohn (regular visiting fellow at the Gulbenkian Science Institute, Oeiras, Portugal.)
{"title":"The biology of recognitive repertoires","authors":"Melvin Cohn (regular visiting fellow at the Gulbenkian Science Institute, Oeiras, Portugal.)","doi":"10.1016/S0167-5699(00)01677-7","DOIUrl":null,"url":null,"abstract":"<div><p>By examining immunoglobulin (Ig) and T-cell receptor (TCR) gene loci and their rearrangement patterns in many species, and by imposing evolutionary principles, we can determine fundamentals regarding the behavior and properties of recognitive repertoires. A recent meeting<span>*</span> addressed the opposing selection pressures that determine the size of the repertoire, the characterization of specificity and the rules for effector function.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 9","pages":"Pages 433-435"},"PeriodicalIF":0.0000,"publicationDate":"2000-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01677-7","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunology today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167569900016777","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
By examining immunoglobulin (Ig) and T-cell receptor (TCR) gene loci and their rearrangement patterns in many species, and by imposing evolutionary principles, we can determine fundamentals regarding the behavior and properties of recognitive repertoires. A recent meeting* addressed the opposing selection pressures that determine the size of the repertoire, the characterization of specificity and the rules for effector function.
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