{"title":"Proteophosphoglycans of Leishmania","authors":"T. Ilg","doi":"10.1016/S0169-4758(00)01791-9","DOIUrl":null,"url":null,"abstract":"<div><p>Proteophosphoglycans are an expanding family of highly glycosylated Leishmania proteins with many unusual and some unique structural features. The novel protein–glycan linkage in proteophosphoglycans – phosphoglycosylation of Ser by lipophosphoglycan-like structures – emerges as a major form of protein glycosylation in Leishmania. Here, Thomas Ilg reviews the chemical structure, the ultrastructure, the genes and the potential functions of different members of this novel family of parasite glycoproteins.</p></div>","PeriodicalId":80110,"journal":{"name":"Parasitology today (Personal ed.)","volume":"16 11","pages":"Pages 489-497"},"PeriodicalIF":0.0000,"publicationDate":"2000-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0169-4758(00)01791-9","citationCount":"138","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Parasitology today (Personal ed.)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0169475800017919","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 138
Abstract
Proteophosphoglycans are an expanding family of highly glycosylated Leishmania proteins with many unusual and some unique structural features. The novel protein–glycan linkage in proteophosphoglycans – phosphoglycosylation of Ser by lipophosphoglycan-like structures – emerges as a major form of protein glycosylation in Leishmania. Here, Thomas Ilg reviews the chemical structure, the ultrastructure, the genes and the potential functions of different members of this novel family of parasite glycoproteins.
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