Osteopontin (Eta-1) in cell-mediated immunity: teaching an old dog new tricks

Anthony W O'Regan , Gerard J Nau , Geoffrey L Chupp , Jeffrey S Berman
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引用次数: 175

Abstract

Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.

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骨桥蛋白(Eta-1)在细胞免疫中的作用:教老狗新把戏
以前被认为是一种粘附骨基质蛋白,最近的研究表明骨桥蛋白(Eta-1)也是一种新型的含rgd的细胞因子,可以调节早期细胞介导的免疫。与细胞外基质相关的蛋白质可能是免疫反应的重要调节剂。
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