{"title":"A natural history of melanoma: serial gene expression analysis","authors":"Ena Wang, Francesco M. Marincola","doi":"10.1016/S0167-5699(00)01724-2","DOIUrl":null,"url":null,"abstract":"<div><p>Ena Wang and Francesco Marincola propose a novel strategy whereby tumor–host interactions are studied within the melanoma microenvironment by serial gene expression analysis. Methodological constraints and ways to circumvent them are discussed. This approach might improve our understanding of the molecular basis of tumor regression in response to immune manipulation.</p></div>","PeriodicalId":73346,"journal":{"name":"Immunology today","volume":"21 12","pages":"Pages 619-623"},"PeriodicalIF":0.0000,"publicationDate":"2000-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0167-5699(00)01724-2","citationCount":"68","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Immunology today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0167569900017242","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 68
Abstract
Ena Wang and Francesco Marincola propose a novel strategy whereby tumor–host interactions are studied within the melanoma microenvironment by serial gene expression analysis. Methodological constraints and ways to circumvent them are discussed. This approach might improve our understanding of the molecular basis of tumor regression in response to immune manipulation.
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