Drawbacks of GENEHUNTER for larger pedigrees: application to panic disorder.

American Journal of Medical Genetics Pub Date : 2000-12-04
R Goedken, E Ludington, R Crowe, A J Fyer, S E Hodge, J A Knowles, V J Vieland, M M Weissman
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Abstract

Large pedigrees can pose a problem for GENEHUNTER linkage analysis software. Differences in two-point and multipoint lodscores were observed when comparing GENEHUNTER to other linkage software. Careful consideration must be given when selecting linkage analysis programs. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:781-783, 2000.

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GENEHUNTER对大谱系的缺点:应用于恐慌症。
大型系谱可能会给GENEHUNTER连锁分析软件带来问题。当比较GENEHUNTER和其他链接软件时,观察到两点和多点负载得分的差异。在选择连锁分析程序时必须仔细考虑。点。J. Med. Genet。(Neuropsychiatr。[j] .地理学报(英文版)96:781-783,2000。
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